Botox vs. PDO Twist Threads: What's Right for Deeper Lines?
Our Team
7/30/2025
Botox vs. PDO Twist Threads: What's Right for Deeper Lines?
When it comes to facial rejuvenation, two non-surgical favorites stand out: Botox and PDO Twist Threads. Both are powerful tools for softening wrinkles and restoring a youthful appearance—but they serve very different purposes.
So, how do you know when Botox is no longer enough for deeper lines? When should you consider PDO Threads—or even combine both? Let’s break it down.
What Does Botox Do?
Botox (Botulinum Toxin) is a neuromodulator that temporarily relaxes muscles responsible for dynamic wrinkles—the ones caused by facial expressions like frowning, squinting, or raising your eyebrows. These include:
- Crow’s feet
- Frown lines (the “11s”)
- Forehead lines
Botox smooths these areas by preventing muscle movement, resulting in a more relaxed and refreshed look.
? Best for:
- Fine to moderate expression lines
- Preventative aging in your 20s and 30s
- Smoothing dynamic lines before they become etched into the skin
When Botox Isn’t Enough
As we age, some wrinkles become static—they stick around even when your face is at rest. Botox can soften these lines but may not fully erase them, especially if:
- The lines are deep and etched into the skin
- There is volume loss or skin laxity in the area
- You’ve been using Botox for years but still see residual creases
- That’s when PDO Twist Threads can enter the conversation.
What Are PDO Twist Threads?
PDO (Polydioxanone) Twist Threads are a type of collagen-stimulating thread inserted beneath the skin to lift, support, and rebuild volume in targeted areas. The “twist” configuration adds bulk and structure, making them ideal for:
- Deep nasolabial folds
- Marionette lines
- Accordion lines near the mouth
- Chin wrinkles or jawline softening
These threads not only give an instant plumping effect but also stimulate your skin’s natural collagen over time.
? Best for:
- Static wrinkles and deeper lines
- Skin that needs structure, not just muscle relaxation
- Long-term collagen remodeling
When to Combine Botox and PDO Threads
Sometimes, it’s not either/or—it’s both. In fact, combining Botox and PDO Threads can deliver more comprehensive, natural-looking results.
Combo Approach Works Well For:
- Forehead lines that persist even after Botox
- Deep smile lines with animation and volume loss
- Wrinkles around the mouth that need both softening and support
- Midface aging that needs structure AND expression control
Our provider may use Botox to relax the overactive muscle, and PDO Twist Threads to fill and support the skin where deeper creases live.
Final Thoughts: What’s Right for You?
Choosing between Botox and PDO Threads depends on the type of wrinkle, skin quality, and your treatment goals.
?? If your lines are dynamic and caused by expression: Start with Botox.
?? If your lines are deep, static, and starting to hollow or sag: Consider PDO Twist Threads.
?? For the most natural and complete result: Combine both strategically.
Consult with our experienced injector or aesthetic provider to create a customized plan tailored to your skin’s needs. Aging is multifactorial—your treatment should be too.
Curious if PDO Threads are right for you? Book a FREE consultation with SkinLumi Aesthetics to explore your options. Your most confident skin is just a treatment away.
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