Botox vs. PDO Twist Threads: What's Right for Deeper Lines?

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7/30/2025

Botox vs. PDO Twist Threads: What's Right for Deeper Lines?

When it comes to facial rejuvenation, two non-surgical favorites stand out: Botox and PDO Twist Threads. Both are powerful tools for softening wrinkles and restoring a youthful appearance—but they serve very different purposes.


So, how do you know when Botox is no longer enough for deeper lines? When should you consider PDO Threads—or even combine both? Let’s break it down.


What Does Botox Do?

Botox (Botulinum Toxin) is a neuromodulator that temporarily relaxes muscles responsible for dynamic wrinkles—the ones caused by facial expressions like frowning, squinting, or raising your eyebrows. These include:


  • Crow’s feet
  • Frown lines (the “11s”)
  • Forehead lines


Botox smooths these areas by preventing muscle movement, resulting in a more relaxed and refreshed look.


? Best for:

  • Fine to moderate expression lines
  • Preventative aging in your 20s and 30s
  • Smoothing dynamic lines before they become etched into the skin


When Botox Isn’t Enough

As we age, some wrinkles become static—they stick around even when your face is at rest. Botox can soften these lines but may not fully erase them, especially if:


  • The lines are deep and etched into the skin
  • There is volume loss or skin laxity in the area
  • You’ve been using Botox for years but still see residual creases
  • That’s when PDO Twist Threads can enter the conversation.


What Are PDO Twist Threads?

PDO (Polydioxanone) Twist Threads are a type of collagen-stimulating thread inserted beneath the skin to lift, support, and rebuild volume in targeted areas. The “twist” configuration adds bulk and structure, making them ideal for:


  • Deep nasolabial folds
  • Marionette lines
  • Accordion lines near the mouth
  • Chin wrinkles or jawline softening


These threads not only give an instant plumping effect but also stimulate your skin’s natural collagen over time.


? Best for:


  • Static wrinkles and deeper lines
  • Skin that needs structure, not just muscle relaxation
  • Long-term collagen remodeling


When to Combine Botox and PDO Threads

Sometimes, it’s not either/or—it’s both. In fact, combining Botox and PDO Threads can deliver more comprehensive, natural-looking results.


Combo Approach Works Well For:


  • Forehead lines that persist even after Botox
  • Deep smile lines with animation and volume loss
  • Wrinkles around the mouth that need both softening and support
  • Midface aging that needs structure AND expression control


Our provider may use Botox to relax the overactive muscle, and PDO Twist Threads to fill and support the skin where deeper creases live.


Final Thoughts: What’s Right for You?

Choosing between Botox and PDO Threads depends on the type of wrinkle, skin quality, and your treatment goals.


?? If your lines are dynamic and caused by expression: Start with Botox.

?? If your lines are deep, static, and starting to hollow or sag: Consider PDO Twist Threads.

?? For the most natural and complete result: Combine both strategically.


Consult with our experienced injector or aesthetic provider to create a customized plan tailored to your skin’s needs. Aging is multifactorial—your treatment should be too.


Curious if PDO Threads are right for you? Book a FREE consultation with SkinLumi Aesthetics to explore your options. Your most confident skin is just a treatment away.



I love coming to Skin Lumi! Christina and all the staff there are amazing and I always have such a great experience when I go. I highly recommend coming here for injections. I get masseter injections for TMJ and I absolutely love the results I’ve seen since coming here. They always have availability to work around my schedule as well. Definitely recommend coming here!!!

C.H. Google

Skin Lumi is so luxurious! The feel of the office is beautiful and relaxing! I’ve had facials and a massage here and both were incredible! If you’re looking for somewhere to pamper yourself look no further!

N.A. Google

I really love this place. It is impeccably clean and perfectly and professionally managed by Fay. Cally is seriously the best injector. You will NOT regret having Cally as your injector. Full disclosure, she’s my cousins wife but Cally is SO TALENTED and knowledgeable and professional. Her touch is incredibly light and precise. For me, she has done facial Botox in masseters, chin, forehead and frown lines. I have also had her do subcutaneous threads and some fillers. I’ll never go to anyone else.(But, I assure you this is not a nepotism review! I have been seeing aesthetician injectors for almost 10 years now for tox and moderate fillers. I was going to a different fancy-pants injector in Holladay for YEARS — until that injector got sloppy and kept on messing up and going too deep with the tox needles. My smile was messed up for 6 months. Then I swear that injector and her assistant were high one of the last times I went in and just did a sloppy job so I had her fix what she could and then I never went back.)So, then I decided to give Cally a chance. The first time I had Cally inject my masseters I was shocked — there was almost no pain!! I was so accustomed to it hurting so bad due to my prior injector. Again, if you’re looking for a qualified, professional, skilled, talented injector then Cally’s your girl. And if you want a lovely, relaxing, professional medspa location then Skin Lumi is your spa. 🥰

D.A. Google

If you’ve been considering visiting this spa and/or getting the Sofwave done, do it! The staff was super knowledgeable and super friendly. They didn’t pressure me for more procedures or try to get me to buy skincare products. I was considering getting a mini-facelift, but I learned about Sofwave. I also considered Morpheus 8, but with current lawsuits and melasma issues with ethnic skin, I decided not to go that direction. I was happy to find that Skinlumi offers this procedure. Sofwave wasnt too painful, especially with numbing cream. I immediately noticed a difference in tightness and fine lines, day 1! I’m excited to see the final results in 6 weeks. Best part, no melasma, only 1 treatment needed, and no downtime. My genetic neck lines have dramatically improved, with just 1 session. I didn’t expect results so quickly, so this was a nice surprise. Cally was my nurse. She was very patient and listened to my concerns and addressed them during my procedure. Faye was so sweet and helped me find an eye cream. She even offered a refund within 2 weeks if the product didn’t work for my sensitive skin, which is really unheard of in a med spa. I’m definitely going back for my hydrafacials and other asthetic needs.

J.N. Google

I’ve had two HydraFacials and a dermaplaning treatment at Skinlumi, and I couldn’t be happier with my experience! Marlee is incredibly sweet and extremely knowledgeable—she truly takes the time to assess my skin’s needs and adjusts each treatment accordingly. From my first appointment to the second, she made thoughtful modifications based on how my skin was doing, which shows her attention to detail and professionalism. My skin always looks and feels amazing after my visits, and I genuinely look forward to my next treatment. Highly recommend Skinlumi!

R.T. Google

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